The abbey of Saint-Vaast (or Saint-Vast) de Moreuil () was a Benedictine monastery in Picardy.Paul André Roger, Archives historiques et ecclésiastiques de la Picardie et de l'Artois (Amiens, 1842), p. 163. It was originally a hospice staffed by two or three monks.Alcius Ledieu, Moreuil et son canton (Paris, 1889), pp. 18–19. The monastery chapel was founded by Bernard I, , in 1109 or 1119 and dedicated to the sixth-century saint-bishop Vedast.Karen Gould, The Psalter and Hours of Yolande of Soissons (Mediaeval Academy of America, 1978), p. 18. At first a priory, it was raised to a full abbey in 1140 or 1150. The king had the right to name its abbot.

The lords of Moreuil continued to be patrons of the monastery. The illuminated Psalter–Hours of Yolande de Soissons, wife of Lord Bernard V, contains three celebrations for Saint Vedast: his feast (February 6), his relatio, when his relics were carried in procession (July 15), and his translatio, recalling the transfer of his relics (October 1). Saint-Vaast de Moreuil served as the burial place of the family of the lords of Moreuil and later the Créquy family. In 1574, Cardinal Antoine de Créquy left it a generous legacy. The abbot by that time was crossé et mitré, that is, entitled to wear episcopal vestments. He had six monks under him.

By 1709, the monastery had fallen on hard times and lead illegally scavenged from the tombs was sold to pay debts. The abbot was arrested and in 1711 one of the monks was sent to the galleys. The monastery was transferred to the Congregation of Saint-Maur, about which there was litigation.Albert N. Hamscher, The Conseil Privé and the Parlements in the Age of Louis XIV: A Study in French Absolutism (American Philosophical Society, 1987), p. 124. It continued as a parish church under the Congregation of Saint-Maur. In 1772, it had an annual revenue of 5,000 livres and remitted 200 florins to Rome.

References