McAlpin House may refer to any of the following structures:
Hotel McAlpin, later the McAlpin House, on Broadway in Manhattan, New York McAlpin–Miller House, also known as the McAlpin House, 9 East 90th Street, Manhattan, New York McAlpin–Minot House, also known as the McAlpin House, 11 East 90th Street, Manhattan, New York Champion–McAlpin House, 122–124 West Jones Street, Savannah, Georgia Champion–McAlpin–Fowlkes House, 230 Barnard Street, Savannah, Georgia