Kilcoyne is a surname found in Ireland and the United States. Notable people with this surname include:

Brendan Kilcoyne (born 1967/1968), an Irish football manager and former player Dave Kilcoyne (born 1988), an Irish rugby union player David Kilcoyne (hurler) (born 1962), an Irish hurler Elizabeth Kilcoyne, an American fiction writer Francis Kilcoyne (1901/1902 – 1985), an American professor of English, college president, and Catholic priest Jack Kilcoyne, a former bass player in the American band Mushroomhead from 1993 to 1996 Martin Kilcoyne (born 1968), an American sports anchor Meghan Kilcoyne, an American state politician for Massachusetts