Peirano is an Italian surname. Notable people with the surname include:
Alejandro Peirano (born 1993), Chilean middle-distance runner Miguel Gustavo Peirano (born 1966), Argentine economist and former government minister Miguel Peirano (footballer) (born 1960), former Uruguayan footballer Pablo Peirano (born 1975), Uruguayan football manager and player Pedro Peirano (born 1972), Chilean director, screenwriter, journalist, cartoonist and television producer Irene Peirano Garrison, American philologist and Pope Professor of the Latin Language and Literature
See also Peirano Market, historic building in Ventura, California, United States of America Peyrano