Sophie of Prussia may refer to:
Duchess Sophie of Prussia (1582–1610) Sophia Louise of Mecklenburg-Schwerin (1685–1735), Queen of Prussia Princess Sophia Dorothea of Prussia (1719–1765) Sophia of Prussia (1870–1932), Queen of the Hellenes, wife of King Constantine I Sophie, Princess of Prussia (born 1978) wife of Georg Friedrich, Prince of Prussia
See Sophie Prussia