159 may refer to:
159 (number), the natural number following 158 and preceding 160 AD 159, a year 159 BC, a year 159 (New Jersey bus), United States 159 (telephone number), a UK telephone number UFC 159, a mixed martial arts event held by the Ultimate Fighting Championship Alfa Romeo 159, a compact executive car Alfa Romeo 159, a Grand Prix racing car 159 series, an electric multiple unit rain type Lectionary 159, a Greek manuscript of the New Testament British Rail Class 159, a DMU train used in the UK