Isai Rodriguez (born March 13, 1998) is an American long-distance runner. He competed in track for his local high school in Ringwood, Oklahoma and collegiately for the Oklahoma State Cowboys, graduating in spring 2023 as a multiple-time All American in both track and cross-country. He won the gold medal in the 10,000 m at the 2023 Pan American Games.

Personal bests Outdoor 1500 metres – 3:44.65 (Fayetteville 2023) 3000 metres – 7:58.57 (Ames, IA 2022) 5000 metres – 13:41.02 (Oxford, MS 2021) 10,000 metres – 27:52.92 (Eugene, OR 2021) Indoor Mile – 4:05.64 (Fayetteville 2019) 3000 metres – 7:54.33 (Seattle 2019) 5000 metres – 13:25.84 (Boston 2022)

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