The mitochondrial pyruvate carriers are composed of:
Mitochondrial pyruvate carrier 1 Mitochondrial pyruvate carrier 2
The pyruvate carriers are involved in mitochondrial metabolism but it is possible to compensate for their loss of function. They have been studied for a role in cardiac stress adaption.
Inhibitors MPC inhibitors include drugs like UK-5099 (JXL001), suvomipic (PP405; JXL069), and JXL082.
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