Tharsis is a Volcanic Plateau on Mars, sometimes called the Tharsis Bulge; the name is a greco-roman transliteration of the biblical Tarshish.

Tharsis may also refer to:

Places

Mars Tharsis quadrangle, a quadrangle map of Mars Tharsis Tholus, a volcano on Mars Tharsis Montes, three large shield volcanoes on Mars

Spain Tharsis-La Zarza mining basin, a Spanish mining area colloquially known as the Tharsis mines Tharsis, Huelva, a village in Andalusia, Spain

Industry Tharsis railway line, a former industrial railway in Spain Tharsis Sulphur and Copper Company Limited, a former British mining company that operated in Spain

Arts Tharsis (video game), a 2016 strategy video game developed by Choice Provisions Reges Tharsis, a Latin motet and antiphon title

Zoology Tharsis (fish), an extinct genus of late Jurassic fish