L2E may refer to:
L2: Empuraan (film), an Indian Malayalam-language action-thriller film Haplogroup L2e, a human mitochondrial haplogroup from West Africa Category L2e, a European vehicle category Postal Code L2E, a Canadian postal code for Niagara Falls, Ontario; see List of postal codes of Canada: L
See also
12E (disambiguation)
L2 (disambiguation) 2E (disambiguation)