L2E may refer to:

L2: Empuraan (film), an Indian Malayalam-language action-thriller film Haplogroup L2e, a human mitochondrial haplogroup from West Africa Category L2e, a European vehicle category Postal Code L2E, a Canadian postal code for Niagara Falls, Ontario; see List of postal codes of Canada: L

See also

12E (disambiguation)

L2 (disambiguation) 2E (disambiguation)