Ufimtsev/Ufimtseva is a Russian surname. Notable people with the surname include:
Anatoly Ufimtsev (1880–1936), Russian engineer Anatoly Ufimtsev (chess player) (1914–2000), Kazakh chess player Irina Ufimtseva (born 1985), Russian Olympics freestyle swimmer Pyotr Ufimtsev (born 1931), Soviet/Russian physicist