Tuifua, Tuifu'a, or Tuʻifua is a surname. Notable people with the surname include:
Isaia Tuifua (born 1987), Samoan rugby union player Leyla Tuifua (born 1986), French volleyball player Taiasina Tuifua (born 1984), Samoan rugby union player Tevita Tuʻifua (born 1975), Tongan rugby union player