MWO may refer to:

Master warrant officer, a military rank in the Canadian Forces Max Watts Out, a non-standard unit of power rating, aka Units Watts Out (UWO) MechWarrior Online, a vehicular combat video game Media Whores Online, a defunct left-wing blog Meyer–Womble Observatory, an astronomical observatory near Mount Evans, Colorado, USA Middletown Regional Airport, Military William Order, or named Military Order of William, the oldest and highest honour of the Netherlands Mount Washington Observatory, a scientific and educational institution with a weather observation station at Mount Washington in New Hampshire Mount Wilson Observatory, an astronomical observatory in Los Angeles County, California, USA