Mike Esposito may refer to:
Mike Esposito (American football) (born 1953), running back for the Atlanta Falcons Mike Esposito (baseball) (born 1981), pitcher for the Colorado Rockies Mike Esposito (comics) (1927–2010), comic book artist, writer and publisher Mike Esposito, lead guitarist for the rock music group Blues Magoos
See also Michael Esposito (disambiguation)