DuPont High School may refer to: Alexis I. duPont High School, high school in Greenville, Delaware DuPont de Nemours Private School, former name of the International School of Luxembourg DuPont High School (West Virginia), defunct high school in Dupont City, West Virginia duPont Manual High School, high school in Louisville, Kentucky P. S. Dupont High School, defunct high school in Wilmington, Delaware