James Milligan may refer to:
James Milligan, Lord Milligan (1934–2005), Scottish lawyer and judge James Milligan (politician) (born 1978), Australian politician James Milligan (singer) (1928–1961), Canadian opera and concert singer James Milligan, a character from the 1932 play Dirty Work by Ben Travers
See also Jamie Milligan (born 1980), English footballer James Milliken (disambiguation)