This is a list of duels in the United States, which in their day were often called affrays or .

May 16, 1777: Button Gwinnett, a signer of the Declaration of Independence, dueled his political opponent Lachlan McIntosh; both were wounded, and Gwinnett died three days later.

July 4, 1778: John Cadwalader, a brigadier General in the Continental Army challenged Thomas Conway, a former general in the same, to a duel. Cadwalader was a supporter of George Washington's and was angered by what he perceived as Conway's disloyal conduct to Washington as a member of the Conway Cabal. The duel was fought with pistols. Cadwalader's shot struck Conway in the mouth and passed through the back of his head. Conway miraculously survived and went on to apologize to Washington. August 30, 1778: Robert Howe, an officer in the Continental Army, shot Christopher Gadsden, a politician from South Carolina, in the ear during a duel.

December 24, 1778: John Laurens dueled fellow Continental Army officer General Charles Lee. Lee was wounded and Laurens was unharmed. Lee had previously participated in a duel while working as a mercenary in Poland in 1765, in which he was wounded and his opponent killed. June 22, 1793: James Lamberton shot and killed John Duncan in a duel in Carlisle, Pennsylvania; Duncan was the father of future Natchez nabob Stephen Duncan and brother of future Pennsylvania chief justice Thomas Duncan. February 3, 1801: Future U.S. Senator John Rowan shot and killed Dr. James Chambers in the second fire of a duel in Bardstown, Kentucky. Future Secretary of the Treasury George M. Bibb was Rowan's second. November 24, 1801: Philip Hamilton, son of the former U.S. Secretary of Treasury, dueled George I. Eacker; Hamilton was killed. September 5, 1802: John Stanly shot and killed Founding Father and former North Carolina Governor Richard Dobbs Spaight in a duel in New Bern. July 11, 1804: U.S. Vice President Aaron Burr, while in office, dueled former U.S. Secretary of the Treasury Alexander Hamilton; Hamilton was killed.

May 30, 1806: Andrew Jackson and Charles Dickinson. Dickinson was killed, and Jackson wounded. Upon his inauguration to the presidency in 1829, Jackson became the only U.S. president to have killed a man in a duel.

November 30, 1806: Plantation owner and militia officer Benjamin Farar Jr. and merchant and militia officer Ferdinand L. Claiborne dueled at the Vidalia sandbar on the Mississippi River. January 19, 1819: Kentuckians Humphrey Marshall and Henry Clay dueled across the state line in Indiana; Clay was shot in the thigh on the third fire. September 25, 1810: Lawyer and future Louisiana state legislator Stephen A. Hopkins shot recently resigned U.S. attorney for Louisiana Philip Grymes through the chest in a duel at Manchac, West Florida."Duels" Newspapers.com. Richmond Enquirer, October 2, 1810. https://www.newspapers.com/article/richmond-enquirer-duels/192557598/. July 7, 1811: George Poindexter and Abijah Hunt dueled in Mississippi Territory; Hunt died of his wounds on July 10. 1814 or 1815: Current and past United States Attorneys for the District of Louisiana John Dick and John Grymes dueled over Grymes' private-practice work for the slave-smuggling privateers the Lafitte brothers; the duel was presumably in the vicinity of New Orleans, both parties reportedly took bullets to the leg. August 12, 1817: Thomas Hart Benton and Charles Lucas, attorneys on opposite sides of a court battle, dueled on the famous Bloody Island after Lucas challenged Benton's right to vote and Benton accused Lucas of being a "puppy"; Lucas was shot in the throat and Benton shot in the leg, upon which Benton released Lucas from his obligation. September 27, 1817: Benton and Lucas rematch, again on Bloody Island; Benton challenged Lucas after Lucas said the first fight at was unfair because Benton was a better shot. Benton killed Lucas at nine feet and was unhurt. July 16, 1819: Subsequent to an argument at a militia muster on the Fourth of July, Kentucky militia general Jacob Holman and militia colonel Francis G. Waring dueled in Franklin County, Kentucky. Waring was killed instantly, Holman was shot in the hip and disabled for life. March 22, 1820: Stephen Decatur and James Barron dueled; Decatur was killed. June 30, 1823: Joshua Barton and Thomas C. Rector dueled on Bloody Island. Barton's brother, Senator David Barton, sought to block the reappointment of Rector's brother, William Rector, to the position of surveyor general for Missouri, Illinois, and Arkansas. Barton was killed and Rector unhurt. September 1825: Planter and state legislator John Joor dueled Mississippi state judge Joshua Child at Woodville, Mississippi; both "severely" wounded but survived. April 26, 1826: Henry Clay and John Randolph of Roanoke dueled at Pimmit Run, Virginia. Both men were unhurt. September 22, 1826: U.S. Representative Sam Houston of Tennessee severely wounded General William A. White in a pistol duel near Franklin, Kentucky, over the patronage political appointment of the Nashville Postmaster. September 19, 1827: A duel between Samuel Levi Wells III and Dr. Thomas Harris Maddox turned into a brawl involving notable figures such as Jim Bowie.

October 29, 1827: Robert Crittenden of Kentucky killed Henry Wharton Conway of Tennessee in Arkansas Territory; the duel resulted from charges of corruption made during a campaign for territorial office. November 5, 1827: North Carolina Congressmen Robert B. Vance and Samuel Carson dueled at the Saluda Gap; Vance died of his wounds the following day. January 25, 1828: George W. Crawford, then attorney general for the state of Georgia, killed Georgia state legislator member Thomas E. Burnside (Ambrose Burnside's uncle) in a duel, answering Crawford's challenge over published defamation of Crawford's father which Burnside had written.

1829: Judge Isaac Caldwell dueled John R. Peyton on the Robinson Road in Mississippi, after Peyton cast the deciding vote that established Jackson as state capital over Clinton. "Both men escaped uninjured." August 26, 1831: Thomas Biddle and Missouri Congressman Spencer Darwin Pettis dueled on the Mississippi's Bloody Island. Biddle challenged Pettis for comments about Biddle's brother, Nicholas Biddle, who was president of the bank of the United States. Both men were mortally wounded after firing from five feet. January 23, 1832: Major J. T. Camp killed Georgia state Senator Sowell Woolfolk in a duel near Columbus, Georgia. August 10, 1832: Savannah physician Philip Minis shot and killed Georgia state legislator James Stark, after which Minis claimed that a valid duel had occurred. Minis also claimed his right to self-defense, saying he had not agreed to the duel and that he shot Stark to save his own life. Minis was found not guilty by a jury. While it is not clearly eligible to be on this list, the deceased had claimed his shooting and threatening fell under the law of duels, which is legally giving permission for his opponent to take shelter in the law of duels. September 25, 1832: James Westcott and Thomas Baltzell; Baltzell unhurt, Westcott injured but survived to become a U.S. Senator. July 14, 1834: Alexander Keith McClung kills Mississippi state representative Augustus Albert Allen in a duel at Jackson. January 12, 1836: Mississippi judge Isaac Caldwell killed by Samuel Gwin of the Government Land Office in Clinton, Mississippi; Gwin died in 1838 in part due injuries suffered in the same duel. February 5, 1837: Texan brigadier general Albert Sidney Johnston was shot in a duel over military position with Felix Huston. February 24, 1838: U.S. Representative from Kentucky William Jordan Graves killed U.S. Representative from Maine Jonathan Cilley in a pistol duel. Afterwards, Congress passed a law making it illegal to issue or accept a duel challenge in Washington, D.C.Jonathan Cilley: Maine Martyr to the Code Duello December 12, 1839: Florida militia brigadier general Leigh Read and Colonel Augustus A. Alston, a Whig Party leader, dueled with rifles at 15 paces. Read had been challenged twice by Alston, an overconfident duelist, and unexpectedly killed Alston."Deadly Game Of Politics Stole Read's Immortality", August 22, 1999, \\Jim Robison, Orlando Sentinel Tallahassee Mayor Francis Eppes (as it happens, Thomas Jefferson's grandson) was elected in large part to put down dueling and other lawlessness in the territory. Read was assassinated by Alston's brother in April 1841. September 18, 1839: Pierre Bossier killed Francois Gainnie in a duel in Louisiana. September 22, 1842: Abraham Lincoln, at the time an Illinois state legislator, accepted a challenge to a duel by Illinois state auditor James Shields. Lincoln apparently had published an inflammatory letter in a Springfield newspaper, the Sangamo Journal, that poked fun at Shields. Taking offense, Shields demanded "satisfaction" and the incident escalated with the two parties meeting on a Missouri island called Bloody Island, near Alton, Illinois, for the duel. Just prior to engaging in combat, the two participants' seconds intervened and were able to convince the two men to cease hostilities, on the grounds that Lincoln had not written the letters."Abraham Lincoln Prepares to Fight a Saber Duel", originally published in Civil War Times magazine July 26, 1847: Albert Pike and John Selden Roane dueled, resulting in a draw, with no injuries. August 20, 1852: Newspaper editors John L. Marling and Felix Zellicoffer duel in Nashville over the presidential election; both were slightly injured and survived. June 1, 1853: U.S. Senator William McKendree Gwin and U.S. Congressman J. W. McCorkle dueled, with no injuries. August 26, 1856: Benjamin Gratz Brown and Thomas C. Reynolds dueled on Bloody Island, in what would be called the "Duel of the Governors". Brown was then the abolitionist editor of the St. Louis Democrat and Reynolds a pro-slavery St. Louis district attorney. Brown was shot in the leg, which caused him to limp for the rest of his life, while Reynolds was unhurt. Brown would later become the Union-sanctioned governor of Missouri and Reynolds a Confederate governor of Missouri. May 17, 1859: Henry Gray Vick and James Stith duel with Kentucky rifles four days before Vick's wedding; Vick killed on the first fire. Possibly took place on grounds of Holly's Garden. Last duel in Mobile, Alabama.François Ludger Diard, 'The Vick–Stith Duel,' October 17, 1936, identification no. 0149-5252, Federal Writers' Project no. 2661, Mobile District 6, WPA Alabama Writers' Project Collection, Alabama Department of Archives and History, Montgomery, Alabama. September 13, 1859: U.S. Senator David C. Broderick and former Chief Justice of the Supreme Court of California David S. Terry dueled; Terry killed Broderick.

September 5, 1862: Confederate major Alfred M. Rhett, son of Fire-Eater Robert Barnwell Rhett, shot and killed Confederate colonel William Ransom Colhoun (a kinsman of John C. Calhoun), his commanding officer at Fort Sumter. September 6, 1863: Brig. Gen. Lucius Marshall Walker, the nephew of President James K. Polk, and General John Sapington Marmaduke, the future governor of Missouri, dueled over differences on the Confederate battlefield at the battles of Helena and Reed's Bridge in Arkansas. The duel took place at 6 am near the north bank of the Arkansas River, just outside Little Rock (now within eyesight of the Clinton Presidential Library). Both men missed their first shots, but Marmaduke mortally wounded Walker with his second shot. Walker died the next day.

July 21, 1865: "Wild Bill" Hickok and Davis Tutt, dueled in Springfield, Missouri. Hickok had lost a pocket watch to Tutt in a card game, and when he demanded its return, Tutt refused. Tutt was shot and killed. The confrontation is often remembered as the first instance of two gunmen participating in a quick-draw duel.Famous Wild West Duel: Wild Bill Hickok vs. Davis Tutt