Frisco Depot or Frisco Station may refer to one of several depot or stations of the former St. Louis and San Francisco Railway (also known as the Frisco Lines).
Fayetteville station (St. Louis–San Francisco Railway) in Fayetteville, Arkansas St. Louis-San Francisco Railroad Depot (Poplar Bluff, Missouri) Antlers Frisco Depot and Antlers Spring in Antler, Oklahoma Idabel station in Oklahoma St. Louis and San Francisco Railway Depot (Comanche, Texas)
Other uses Frisco Station, Texas is a mixed use development in Frisco, Texas "Frisco Depot", a song by Mickey Newbury on his 1971 album Frisco Mabel Joy.