Marie-Denise is a French feminine given name. Notable people with the name include:
Marie-Denise Douyon (born 1961), Canadian painter Marie-Denise Fabien Jean-Louis (born 1944), Haitian physician and politician Marie Denise Pelletier (born 1960), Canadian singer Marie-Denise Villers (1774–1821), French painter Marie-Denise Vriot (1742–1817), French stage actress
See also
Marie (given name) Denise (given name)