This is a list of notable disease outbreaks in the United States:
1700s 1775–1782 North American smallpox epidemic 1789–1790 influenza epidemic 1793 Philadelphia yellow fever epidemic
1800s 1837 Great Plains smallpox epidemic 1849-1850 Tennessee cholera epidemic 1853 yellow fever epidemicCampbell, Heather G. (1999) "The Yellow Pestilence: A Comparative Study of the 1853 Yellow Fever
Epidemic in New Orleans and the Galveston, Texas Scourge of 1867," East Texas Historical Journal: Vol. 37: Iss. 1, Article 8. https://scholarworks.sfasu.edu/ethj/vol37/iss1/8 1862 Pacific Northwest smallpox epidemic 1876 yellow fever epidemic 1878 Lower Mississippi Valley yellow fever epidemic
1900s 1900–1904 San Francisco plague epidemic 1916 New York City polio epidemic 1918–1930 Encephalitis lethargica epidemic 1924 Los Angeles pneumonic plague outbreak 1924–1925 Minnesota smallpox epidemic 1947 New York City smallpox outbreak 1962-1965 rubella epidemic 1976 Philadelphia Legionnaires' disease outbreak 1976 swine flu outbreak 1987 Carroll County cryptosporidiosis outbreak 1990–1991 Philadelphia measles outbreak 1993 Four Corners hantavirus outbreak 1992–1993 Jack in the Box E. coli outbreak 1993 Milwaukee cryptosporidiosis outbreak 1996 Odwalla E. coli outbreak
2000s 2003 Chi-Chi's hepatitis A outbreak 2003 Midwest monkeypox outbreak 2006 North American E. coli O157:H7 outbreak in spinach 2006 North American E. coli O157:H7 outbreaks 2008 United States salmonellosis outbreak 2009 swine flu pandemic in the United States 2011 United States listeriosis outbreak 2012 outbreak of Salmonella 2012–2013 United States flu season 2014 enterovirus D68 outbreak 2015 Bronx Legionnaires' disease outbreaks 2015 United States E. coli outbreak 2015 United States H5N2 outbreak 2016 United States Elizabethkingia outbreak 2017–2018 United States flu season 2018 United States adenovirus outbreak 2019 New York measles outbreak 2019 Pacific Northwest measles outbreak 2019 United States hepatitis A outbreak 2019–2020 United States flu season 2020-2023 COVID-19 (national emergency terminated April 2023) 2022–2023 mpox outbreak in New York (state) 2022–2023 United States P. aeruginosa outbreak in eye drops
See also List of epidemics and pandemics List of disasters in the United States by death toll
References