The 1994 Prairie View A&M Panthers football team represented Prairie View A&M University as a member of the Southwestern Athletic Conference (SWAC) during the 1994 NCAA Division I-AA football season. Led by fourth-year head coach Ronald Beard, the Panthers compiled an overall record of 0–11, with a mark of 0–7 in conference play, and finished eighth in the SWAC.

Their loss against Jackson State marked their 45th loss in a row to set the longest losing streak in Division I-AA. The previous record was 44 consecutive losses by Columbia from 1983 to 1988.

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