Prell is a surname. Notable people with the surname include:
Allan Prell (1937–2016), American talk radio host Bally Prell (1922–1982), German performer, humorous singer, and folk singer Donald Prell (1924–2020), American World War II veteran, venture capitalist and futurist Heinrich Prell (1888–1962), German zoologist Hermann Prell (1854–1922), German history painter, sculptor and professor Karen Prell (born 1959), American puppeteer and animator Milton Prell (1905–1974), American hotel owner and developer
See also Prill (surname)