Red Blooded American Girl is a 1990 Canadian science fiction horror film written by Allan Moyle, directed by David Blyth and starring Andrew Stevens, Heather Thomas, Christopher Plummer and Kim Coates.

Premise A young woman is transformed into a vampire by a virus. The vampire doctor who's treating her hires a young scientist to find a cure. He and the girl fall for each other hard, but she, mad from hunger, escapes to wreak havoc on the city.

Cast Andrew Stevens as Owen Augustus Urban III Heather Thomas as Paula Bukowsky Christopher Plummer as Dr. John Alcore Kim Coates as Dennis Lydie Denier as Rebecca Murrin Andrew Jackson as Donald

Reception TV Guide gave a mixed review: "Plummer's commanding presence gives the enterprise a shot of class, but it needed a massive transfusion."

Fred Haeseker of the Calgary Herald awarded the film two stars and praised Plummer's performance.

Sequel An in name only sequel titled Red-Blooded American Girl II was released in 1997, with none of the original's cast and a different storyline; only director David Blyth connects the two films. In his 2015 book Spinegrinder: The Movies Most Critics Won’t Write About, author Clive Davies called it a "a useless road movie that isn't really a sequel".

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