Uxbridge by-election may refer to several elections to the UK parliament:
1915 Uxbridge by-election, following the death of Charles Mills in the First World War 1972 Uxbridge by-election, following the death of Charles Curran 1997 Uxbridge by-election, following the death of Michael Shersby a week after the general election 2023 Uxbridge and South Ruislip by-election, following the resignation of Boris Johnson