Santibáñez or Santibanez is a surname. Notable people with the surname include:
Jorge Santibáñez Ceardi (1934–2020), Chilean politician and lawyer Bárbara Santibáñez (born 1996), Chilean footballer Carlos Santibáñez (born 1986), Argentine football midfielder Edwin Santibáñez (born 1980), Mexican retired footballer Emanuelle Silva Santibanez, Chilean road skater Ignacio Santibáñez (1512–1598), the first Roman Catholic Archbishop of Manila Joaquín Santibáñez (born 1952), Mexican former Olympic swimmer José Daniel Santibáñez (born 1959), Ecuadorian science fiction novelist and comic book writer Katia Santibañez (born 1964), French-American multidisciplinary abstract artist Luis Santibáñez (1936–2008), Chilean football manager Mario Santibáñez (born 1950), Mexican Olympic swimmer Marisela Santibáñez (born 1975), Chilean actress, presenter, politician of the Communist Party Rogelio Hernández Santibáñez (born 1934), Spanish racing cyclist Tamara Santibañez (born 1987), American visual artist, and tattoo artist Francisco Gómez de Quevedo y Santibáñez Villegas, Knight of the Order of Santiago (1580–1645), Spanish nobleman, politician, writer
See also Estadio Municipal Roberto Bravo Santibáñez, multi-use stadium in Melipilla, Chile Santi Ibáñez