Wackerle is a surname. Notable people with the surname include:
Anton Wackerle (born 1938), German bobsledder Hilmar Wäckerle (1899-1941), German concentration camp commandant and Waffen-SS officer Joseph Wackerle (1880–1959), German sculptor Sylvester Wackerle (1908–1978), German bobsledder Sylvester Wackerle (ice hockey) (born 1937), German ice hockey player