Alfeo is a male Italian given name, and sometimes a surname, derived from the Greek Alphaios (Αλφαιος), itself based on Greek alphe (ἀλφὴ). Notable people with the name include:

Given name Alfeo (Ludovico Ariosto character), character from the Orlando Furioso Alfeo Brandimarte, Italian naval officer Alfeo Brum, Uruguayan politician Alfeo Mizzau, Italian politician