Fernando Antonio de Jesús Guzmán Mata (29 November 1921 – 26 October 1993) was a Costa Rican physician and politician who served as Second Vice President of Costa Rica from 1974 to 1978. A member of the National Liberation Party, he previously served as a deputy in the Legislative Assembly from 1966 to 1970.

Alongside Jorge Luis Villanueva Badilla he created the Costa Rica Institute of Technology.

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