Rio is a surname which may refer to:

Al Rio (1962–2012), Brazilian comic book artist Alexis-François Rio (1797–1874), French author and art critic Frank Rio (1895–1935), Co-founder and crime boss of the Chicago Outfit Michel Rio (born 1945), French writer and novelist Michel Rio (footballer) (born 1963), French former footballer Neiphiu Rio (born 1950), Indian politician Patrice Rio (born 1948), former French footballer Ricardo Rio (born 1972), is a Portuguese economist and politician, current mayor of Braga Rui Rio (born 1957), Is a Portuguese economist and politician, was Mayor of Porto Zhaleo Rio, 21st century Indian politician, brother of Neiphiu Rio

See also Riario an Italian noble family Rio (disambiguation) Del Rio (disambiguation) Ríos (disambiguation)