Di or di Giacomo is a surname. Notable people with the surname include:
Andrea di Niccolò di Giacomo (1440–1514), Italian painter Daniela di Giacomo (born 1985), Venezuelan TV host, journalist, radio host, model and beauty queen Federica Di Giacomo, director and writer of the 2016 documentary Libera Nos Francesco Di Giacomo (1947–2014), Italian singer and lyricist Franco Di Giacomo (1932–2016), Italian cinematographer Gegè Di Giacomo (1918–2005), Italian singer and drummer, nephew of Savatore Di Giacomo Luis Di Giacomo (born 1954), Argentine psychiatrist and politician Marina di Giacomo (born 1976), Argentine field hockey player Paul di Giacomo (born 1982), Scottish footballer Salvatore Di Giacomo (1860–1934), Italian poet, songwriter, playwright and fascist
See also De Giacomo, a cognate