William Fitzhugh (1741–1809) was an American planter, legislator, and patriot.

William Fitzhugh may also refer to:

William FitzHugh, 4th Baron FitzHugh (1399–1452), English nobleman and member of parliament William Henry Fitzhugh (1792–1830), Virginia planter and politician William F. Fitzhugh (1818–1883), American Confederate soldier and Texas Ranger William W. Fitzhugh (born 1943), American archaeologist and anthropologist William Fitzhugh (MP) (1757–1842), English politician and member of parliament

See also W. Fitzhugh Brundage (born 1959), American historian William Henry Fitzhugh Lee (1837–1891), American planter, general, and politician