The list of Puerto Rico hurricanes from the 21st century has been marked by several devastating North Atlantic hurricanes, tropical or subtropical cyclones, their remnants, or their precursors have affected the U.S. territory of Puerto Rico. Every year included has at least one tropical cyclone affecting the territory.

The strongest hurricane to hit the territory during the time period was Hurricane Maria, which was a Category 4, on the Saffir–Simpson scale, the second-highest category on the scale. Maria was the strongest hurricane to strike the territory since 1928 Okeechobee hurricane.

2000

August 23 – Hurricane Debby dropped up to 12 inches (30.5 mm) of rainfall across Puerto Rico in less than 48 hours, causing mudslides and damage to bridges and roads. There were 406 homes affected from the flooding, 5 of which were moderate to severely damaged. Losses in Puerto Rico reached $501,000, primarily in the Caguas municipality. The storm was also indirectly responsible for the death of a 78-year-old man who fell while trying to remove a satellite dish from the roof of his home. September 17–18 – The wave to Tropical Storm Helene passed to the south of Puerto Rico on September 17 and 18. Across the southern and eastern portion of the island, the system produced of rainfall, which resulted in flash flooding and mudslides. One house was destroyed and more than 100 houses were affected in Ponce, forcing several families to evacuate. The flooding also destroyed a bridge in Guayama and made many roads impassable. Damage on the island was estimated at $100,000 (2000 USD).

2001

August 18 - the outer rainbands of Tropical Storm Chantal produced light to moderate rainfall across Puerto Rico and the United States Virgin Islands. In Puerto Rico, the highest rainfall total was in Rio Piedras. August 22–23 – Tropical Storm Dean dropped heavy rainfall across Puerto Rico, peaking at 12.7 inches (322 mm) in Salinas. The passage of Dean resulted in widespread flooding in eastern and southern Puerto Rico, collapsing two bridges and one road. Several highways were under water, and one car was swept away by the floodwaters. The four inside the vehicle were later rescued and unharmed. Throughout the island, about 1,320 houses were flooded, and two houses experienced collapsed roofs. The rains left various towns without power or water. Two people were injured in Peñuelas, and three were injured in Nagüabo when the ceiling of a day care center collapsed, though no deaths occurred on the island. One airline canceled seventeen flights in and out of the island, and one cruise line was required to alter its path to both Dean and earlier due to Tropical Storm Chantal. Damage in Puerto Rico totaled to $7.7 million (2001 USD, $9.4 million 2008 USD), of which $2.1 million (2001 USD, $2.6 million 2008 USD) was from agricultural damage.

2003

August 18 - Tropical Depression Nine caused moderate rainfall in Puerto Rico, where 2 to 3 inches (50 to 75 mm) of precipitation were recorded. Damage in Puerto Rico totaled $20,000 (2003 USD$,  USD). October 10–11 - Tropical Storm Mindy caused rainfall levels that reached up to near Ponce, Puerto Rico. Strong winds left around 29,000 people without power in northeastern Puerto Rico. The rainfall wrecked bridges in Las Piedras and Guayama, and led to flooded streams, downed trees, and rockslides that closed four roads. One car was swept away, and a few houses were flooded. The damage total was at least $46,000 (2003 USD). December 8–10 - Tropical Storm Odette caused moderate rainfall across Puerto Rico. Rainfall in Puerto Rico was heaviest in the southeast, where a peak of 8.73 in (221.74 mm) was recorded in Jajome Alto. Odette's rainfall caused flooding throughout Puerto Rico's rivers. The river flooding destroyed three bridges, resulting in $20,000 in damages (2003 USD).

2004

September 15–16 - Upon striking Puerto Rico, Tropical Storm Jeanne produced tropical storm force winds in portions of the island. A NWS employee reported sustained winds of , with gusts to in Salinas along the southern coast. In Cayey, located in the center of the island, a 72 mph (117 km/h) gust was reported, just shy of hurricane force. Additionally, the Luis Muñoz Marín International Airport in San Juan reported sustained winds of 49 mph (80 km/h). In Yabucoa, the winds killed one woman after she was flung into a wall. A total of 8 were killed, and damage totaled $169.5 million (2004 USD), making it the most damaging tropical cyclone since Hurricane Georges in 1998.

2006

August 3 - Tropical Storm Chris dropped light rainfall in Puerto Rico, peaking at 3.09 inches (78 mm) in Fajardo. The rainfall from the storm caused the Fajardo River to overflow its banks, which temporarily closed a highway in the northeastern portion of the island.

2007

October 26 - The precursor of Hurricane Noel dropped heavy rainfall across Puerto Rico for several days, leaving grounds saturated and causing surface runoff. Precipitation peaked at at Carite Lake. Flash flooding was reported in Carolina, and a mudslide occurred in Utuado. Flooding occurred along several rivers, including the Río de la Plata, with a reading of above flood stage at Toa Baja reported late on October 27. In response to high water levels, officials opened dam gates along the Río de la Plata and the Río Carraízo. There were no official reports of fatalities. December 11–12 - Tropical Storm Olga dropped light to moderate precipitation across Puerto Rico, peaking at 11.13 inches (283 mm) near Ponce. The rainfall increased levels along several rivers across the island, including the Río Grande de Arecibo which was reported at several feet above flood stage. Its passage left about 79,000 people without power and 144,000 without water. In the northern portion of the island, the rainfall caused a mudslides that buried an automobile, which killed its driver.

2008

August 30–31 - Some areas of northeastern Puerto Rico observed of rain in only 24 hours due to Tropical Storm Hanna. As a result, many rivers exceeded their banks and several mudslides were reported. A number of streets were inundated and later closed. The Westin Rio Mar Golf Club course in Río Grande was also flooded. On the western side of the island in Añasco, residents fled their homes for shelters. September 21–23 - The precursor to Hurricane Kyle produced record-breaking rains over Puerto Rico from September 21 to 23. With isolated maxima in excess of 30 inches (760 mm), rivers breached their flood walls and flooded low-lying areas. Damage to agriculture on the island was estimated to be $23 million and structural damage was estimated at $25 million, for a total of $48 million. October 13–16 - The precedent to Hurricane Omar produced heavy rains over the island, causing minor flooding. After passing by Puerto Rico a second time, Omar produced locally heavy rains, which caused minor street flooding. A man died after he collapsed from cardiac arrest while trying to install storm shutters on his home.

2009

August 17 - Minor rainfall from Tropical Storm Ana triggering minor flooding but little damage. A maximum of of rain fell in Río Grande. The rains caused the Río Fajardo to rise, resulting in the issuance of an alert as officials warned it could overflow its banks. Several streets were temporarily shut down due to flooding, including one tunnel, and three schools had to be evacuated. Throughout the island, roughly 6,000 people were left without power as numerous branches were snapped off trees and knocked down power lines. August 22 - Large, life-threatening swells produced by Hurricane Bill impacted north-facing coastlines of Puerto Rico September 4 - The remnants of Tropical Storm Erika produced significant amounts of rainfall, causing the rivers of La Plata, Loíza and Caguitas to overflow their banks and trigger widespread flooding. A weather station in Naguabo recorded of precipitation. Several other areas recorded upwards of . In the municipality of Guanica, several homes were flooded, leaving $5,000 in damage. The most severe damage took place in the municipality of Las Piedras where $15,000 was reported in flood losses. One river rose to a level of , above flood stage. Damage in Fajardo was estimated at $10,000 after homes were inundated by flood waters. Additionally, flooding in Caguas resulted in $5,000 in damage.

2010

July - The precursor to Tropical Storm Bonnie brought significant rainfall to parts of Puerto Rico and Hispaniola, leading to widespread flooding. In Puerto Rico, one person drowned after being caught in a swollen river. August 30–31 - Heavy rains from Hurricane Earl began to affect Puerto Rico as Hurricane Earl moved closer to the island. Throughout the island, a maximum of of rain fell near Naguabo. In San Juan, of rain fell during the passage of Earl. Dozens of roads were shut down across the island due to flooding and downed power lines. At the height of the storm, roughly 187,000 residences were left without power and 60,000 more were without water. September 7–8 - The remnants of Tropical Storm Gaston produced sporadic rainfall across Puerto Rico, peaking at 3.03 in (76.9 mm) in Naguabo. September 16–21 - Hurricane Igor large swells averaging 9 to 13 ft (2.7 to 4.0 m) in height. Similar conditions affected Puerto Rico where another person drowned. On several occasions, Luquillo was flooded by the surf, though no damage took place. October 5–8 Rain began to pour across several parts of Puerto Rico due to Hurricane Otto, persisting for up to five days in some areas. The greatest amount of rainfall during the six-day period of October 3 to 8 was registered at Rio Portugues in Ponce, with recorded. Subsequent widespread flooding affected at least 295 roads, 14 of which suffered significant damage. In all, damage to road infrastructure was preliminarily estimated at US$6.5 million. In addition, the municipality of Ponce reported copious losses in agriculture, later estimated at US$1.5 million.

2011

August 2–3 While moving south of Puerto Rico, Tropical Storm Emily brought prolonged tropical storm conditions to many parts of the island. The heaviest rainfall occurred in southern regions; Caguas recorded a total of 8.22 in (209 mm) of rain during the storm. High winds damaged an electrical grid, cutting off power to about 18,500 customers. Throughout the island, multiple roads were made impassable by landslides and fallen objects; infrastructural damage surmounted $5 million, according to preliminary estimates. Capital losses were estimated at $55 million. August 21–23 - Across Puerto Rico, heavy rains from Hurricane Irene caused extensive damage to roads while hurricane-force winds toppled many trees and utility poles, which led more than 1 million residences without power. At higher elevations, winds estimated by radar neared . The highest amounts of precipitation fell across eastern parts of the territory; in Gurabo, a peak total of was recorded. The rains continued to fall for hours into the wake of the storm. One driver was killed after their vehicle was caught in swollen currents. Preliminary estimates indicate structural damage could be as high as $500 million (USD), with additional losses due to the three-day labor suspensions pinned at over $60.4 million (USD). September 11–12 - Hurricane Maria effects on the island of Puerto Rico were primarily in the form of heavy rainfall. Flood waters near Patillas, Puerto Rico, destroyed several homes and bridges, causing $1.3 million (2011 USD) in damage. In the surrounding city of Yabucoa, Puerto Rico, heavy rainfall flooded and damaged around 150 homes. Many people were forced to relocate after rainfall and mud filled their homes. Near the city of Naguabo, Puerto Rico, the car of a 60-year-old woman was swept away by flood waters on a road. After becoming tangled in bushes, the woman was able to get out of her car and pulled to safety.

2012