Amphissa may refer to:
Amphissa (city), an alternative writing for Amfissa, a town and a former municipality in Phocis, Greece Amphissa (gastropod), a small sea snails genus in the family Columbellidae Amphissa (mythology), an incest daughter of Aeolus's son, Macareus, with his sister, Canace, in Greek mythology Microvoluta amphissa, a sea snail species