Zelnick is a surname of Jewish origin, meaning either "haberdashery" or "tax collector". Notable people with the surname include:

Mel Zelnick (1924–2008), American jazz drummer Robert Zelnick (1940–2019), American journalist and professor Strauss Zelnick (born 1957), American businessman

See also Aldo Zelnick, a comic novel children's book series Zelnik (surname)