Muciño is a surname. Notable people with the surname include:
Arely Muciño (born 1989), Mexican professional boxer César Muciño (1972–2003), Mexican cyclist Claudia Muciño (born 1971), Mexican former professional tennis player Jennifer Mucino-Fernandez (born 2002), American archer Luis Muciño (born 1936), Mexican former cyclist Octavio Muciño (1950–1974), Mexican professional football player