The Independent Spirit Award for Best Male Performance in a New Scripted Series was one of the annual Independent Spirit Awards to honor an actor who has delivered an outstanding performance in a new scripted series. It was first presented in 2020 with Amit Rahav being the first recipient of the award for his role as Yakov "Yanky" Shapiro in miniseries Unorthodox and the last recipient of the award is Lee Jung-jae for his role as Seong Gi-hun in Squid Game.

In 2022, it was announced that the acting categories would be retired and replaced with two gender neutral categories: Best Lead Performance in a New Scripted Series & Best Supporting Performance in a New Scripted Series.

Winners and nominees 2020s YearNomineesShowRoleNetwork 2020 Amit Rahav Unorthodox Yakov "Yanky" Shapiro Netflix Adam Ali Little America Zain Apple TV+Nicco Annan P-Valley Uncle Clifford StarzConphidance Little America Iwegbuna Apple TV+ Harold Torres ZeroZeroZero Manuel Contreras Prime Video2021 Lee Jung-jae Squid Game Seong Gi-hun NetflixOlly Alexander It's a SinRitchie Tozer Channel 4 Murray Bartlett The White Lotus Armond HBO Michael Greyeyes Rutherford Falls Terry Thomas Peacock Ashley Thomas Them: Covenant Henry Emory Prime Video

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