Santesteban is a surname of Basque origin. People with that name include:

Ane Santesteban (born 1990), Spanish racing cyclist Jesús de Santesteban (1866 — after 1893), Basque pianist and composer, son of José Antonio Jose Agerre Santesteban (1889–1962), Basque writer and politician José Antonio Santesteban (1835–1906), Basque composer, song of José Juan, father of Jesús José Juan Santesteban (1809–1884), Basque composer, father of José Antonio

See also Doneztebe-Santesteban, a town in Navarre, Spain Saint-Esteben Santisteban