Michaelides () is a Greek surname which is a patronym meaning "son of Michael". Notable people with the surname include:
Alekos Michaelides (1933–2008), Cypriot politician Alex Michaelides (born 1977), British Cypriot author and screenwriter Alexis Michaelides (born 1950), Cypriot businessman and politician Andonis Michaelides, known as Mick Karn (1958–2011), English-Cypriot musician and songwriter Andreas Michaelides (born 1952), Cypriot football manager and politician Efstathios E. Michaelides (born 1955), Greek-American mechanical engineer Konstantinos Michaelides (born 2000), Cypriot footballer Solon Michaelides (1905–1979), Cypriot composer, teacher and musicologist Stavros Michaelides (born 1970), Cypriot swimmer Tony Michaelides (born 1953), British music industry executive Vasilis Michaelides (–1917), Cypriot poet