Paraguaçu is a municipality in the state of Minas Gerais, Brazil.
Paraguaçu or Paraguassu may also refer to:
Geography Paraguaçu Paulista, municipality in the state of São Paulo, Brazil Paraguaçu River, in Bahia state, Brazil Cabaceiras do Paraguaçu, municipality in the state of Bahia, Brazil Cachoeira, also Cachoeira do Paraguaçu, municipality in the state of Bahia, Brazil
People Catarina Paraguaçu (died 1586), Brazilian Tupinambá Indian, Christian visionary, wife of Caramuru Ezequiel Paraguassu (born 1963), Brazilian judoka, competitor at the 1988 and 1992 Summer Olympics