Barbora Krejčíková defeated Iga Świątek in the final, 5–7, 7–6(7–4), 6–3 to win the singles tennis title at the 2022 Ostrava Open. It was Krejčíková's second WTA Tour title in back-to-back weeks, and she ended Świątek's streak of ten consecutive victories in WTA Tour finals. This marked only Świątek's second career loss in a WTA Tour-level final, out of twelve played (the other being at the 2019 Ladies Open Lugano).
Anett Kontaveit was the defending champion, but retired in the second round against Tereza Martincová.
Seeds The top four seeds received a bye into the second round.
Draw
Finals
Top half
Bottom half
Qualifying
Seeds
Qualifiers
Qualifying draw
First qualifier
Second qualifier
Third qualifier
Fourth qualifier
Fifth qualifier
Sixth qualifier
References
Main draw Qualifying draw