Rijksmuseum Boerhaave is a museum of the history of science and medicine, based in Leiden, Netherlands. The museum hosts a collection of historical scientific instruments from all disciplines, but mainly from medicine, physics, and astronomy.

The museum is located in a building that was originally a convent in central Leiden. It includes a reconstructed traditional anatomical theatre. It also has many galleries that include the apparatus with which Heike Kamerlingh Onnes first liquefied helium (in Leiden), the electromagnet equipment used by Wander Johannes de Haas (a Leiden physicist) for his low-temperature research, and an example of the Leiden jar, among many other objects in the extensive collection.

The museum is named after Herman Boerhaave, a Dutch physician and botanist who was famous in Europe for his teaching at Leiden and lived to a great age, receiving brilliant students from all over Europe, including Peter the Great, Voltaire and Linnaeus.

History Boerhaave Museum's history began in 1907, when a Historical Exhibition of Natural Science and Medicine was held in the of Leiden University. The many objects in the exhibition came from all the learned corners of the country. It was a great success and there were immediately calls to set up a permanent science history exhibit.

In 1928 a foundation was initiated by physicist Claude August Crommelin, who worked at Leiden university, for a museum for the history of natural sciences. The aim of the museum was described in the preliminary statutes of the foundation: "the collection of instruments, tools, slides and specimens, documents and other objects, which are important for the history of the natural sciences; to look after these objects, describe them and keep them in a museum which is to be located in Leiden". The sciences to be represented included: Astronomy, Physics, Chemistry, Botany, Zoology, Pharmacy, all medical sciences – including Physiology, Anatomy et cetera, and Mathematics.

In 1931 the museum opened as "The Dutch Historical Museum of the Natural Sciences" (Het Nederlandsch Historisch Natuurwetenschappelijk Museum). To the view of Crommelin, the museum was to become a national museum: the 's Gravesande-Musschenbroek collection would form the starting point, to which collections from other institutes were to be added.

In 1947 the museum, which was in fact a private foundation, became formally a national museum. It was renamed to "The Dutch National Museum for the History of the Natural Sciences" (Rijksmuseum voor de Geschiedenis van Natuurwetenschappen). An advisory board was installed in which members of Dutch universities would take seat. It underlined the ambition to become a national museum, not a museum solely connected to the Leiden University.

Before moving in 1991, the museum was located in the former Boerhaave Laboratory at the Steenstraat 1, Leiden, a building which belonged to the Leiden Academic Hospital (Leiden Academisch Hospital), now part of LUMC, Leiden University Medical Center. This location of the museum now houses the National Museum of Ethnology.

To create better housing the former nunnery of Saint Cecilia was bought by the Government Buildings Agency (Rijksgebouwendienst). This historic building has had various functions over time. The building dates from the early 15th century. The building had become municipal property after the Protestant Reformation and shortly before 1600 was converted into a pest house and lunatic asylum. The Leiden Academic hospital was founded in this location between 1636 and 1639. In 1967, with the prospect of a new location the name of the museum was changed to "Museum Boerhaave". However, it took more than twenty years before the museum finally moved. After extensive restoration and expansion, the building is in use as a museum since 1991.

Rijksmuseum Boerhaave was elected European Museum of the Year 2019. Founded in 1977, this is the oldest and most prestigious museum award in Europe. The international jury praised the completely renewed science and medicine museum in Leiden: "The exceptional public quality of this museum results from its artful approach to communicating science.  Important and beautiful objects are interpreted using the latest technologies and the personal stories of those driven by a passion for the pursuit of knowledge.  The result is science with a human face, inspiring curiosity and amazement as well as engaging a wide public in debates on important scientific and ethical questions issues of our time."

Collection The Boerhaave Museum is running a project to document approx. 3000 objects in its collection online, with pictures and descriptions for every single object. In April 2010 the site featured over 1750 objects, ordered by room and showcase. This overview is in large part based on the museum's online documentation.

The museum has 25 galleries, which are by and large organised chronologically, with thematical subgroupings per gallery.

16th–17th century

0 Museum Foyer

Gapers (wooden heads miming the swallowing of pills) and other shop signs for pharmacies and druggists. Also a 'dictionary of health': a tall book-shaped wooden chest (1660) filled with simples (basic substances used in medicine).

1 Leiden Anatomical Theater

The room shows a reconstruction (1988) of the Theatrum Anatomicum (anatomical theatre) (built 1596). A richly decorated instrument chest (1670) which belonged to the Leiden surgeon's guild. A small collection of objects (largely Egyptian antiquities) that survived from the now gone Leiden Theatrum (one of the oldest museums of Europe ) are shown as well. On the wall three paintings: one depicting the magistrates of the Catharina and Caecilia Hospitals (the latter now houses the museum), a second showing a Prussian peasant from whom a 10-inch sword, swallowed in a drinking bout, has surgically been removed, a third showing renowned surgeon and designer of medical instruments Cornelis Solingen (1680). One of Solingen's inventions (part of the collection) was a screw to unindent a soldiers skull who had been hit by a bullet. Often in those days bullets did not fully penetrate a skull, merely deformed it.

2 Drawn from life

Four large allegoric paintings (± 1610) show in stages how the appreciation of a patient for his physician declines, from being a true savior (Christ) when the illness is at its height to being a devil when the bill is delivered. Three solid figures of Saints Cosmas and Damian, patrons of doctors and pharmacists.

Six anatomical books and drawings (1520–1570) and six books on herbs (1480–1590) testify how in the Renaissance there was an urge to study life diligently and not take traditional beliefs for granted. A large collection of baked and painted apothecary jars (1550–1650) and (often ornamented) cast-iron and bronze mortars (1350–1700).

3 The Golden Age

18th century The following two rooms are dedicated to an era of blossom for the University of Leiden, the oldest university of the Netherlands (founded in 1575).

4 Leiden University: Boerhaave and ‘s Gravensande

This large room is dedicated to physician, botanist and chemist Herman Boerhaave, physicist Willem 's Gravesande and instrument-maker Jan van Musschenbroeck. On display are large globes and a tiny pocket globe (all ~1700), each depicting heaven and earth. A table size planetarium by clock-maker Steven Tracy Mercury shows Venus, Earth with its moon, Mars, Jupiter with four moons and Saturn. There is also a large star atlas.

Air pumps (1670–1730) and demonstration devices, notably several Magdeburg hemispheres, were made to explore the properties of the newly discovered vacuum. Other devices did the same for centrifugal force, collisions and laws of momentum, and gravity.

Hydrometers, an aerometer, a hydrostatic bellows, a balance and steam pump, several table-top fountains all were used to look into hydrostatic pressure, and capillary attraction.

Also shown are a large set of mathematical instruments to measure angles: sectors, a protractor and beam compass.

A collection of balances, levers, tackles demonstrate laws of statics.

A variety of lenses, prisms, a slit, trays and screens explore optics. About ten screw-barrel and compound microscopes (1710–1780) demonstrate how this young science underwent dramatic progress in few years. A variety of curved mirrors, used as anamorphic toys, show how a deliberately distorted image can be restored back to the original.

The room also houses a range of instruments (levers and forceps) used to facilitate childbirth.

Lastly, shown are models of three out of five of Archimedes' so called simple machines (lever, inclined plane, wedge, screw and wheel), several hydrostatic balances to demonstrate Archimedes' law and two tables of forces which demonstrate interactions of forces in a horizontal plane.

5 Leiden University: Linnaeus and Van Musschenbroek

Carl Linnaeus published his famous Systema Naturae in 1735, during his 3-year stay in the Dutch Republic, in which he also earned a degree in medicine, and closely worked together with Boerhaave. At display are paintings of Linnaeus and Boerhaave. Also 18th-century models and scientific measuring instruments: models that demonstrate basic physics principles, and instruments: several antique thermometers, a barometer, a theodolite and several pyrometers. Also two antique globes (one showing the heavens, one earth) and two mirror telescopes. The room is conamed after the brothers van Mussenbroeck: Pieter a professor, credited with the invention of the first capacitor in 1746: the Leyden jar, and Jan a famous instrument maker, who shipped his hand crafted precision thermometers all over Europe.

6 Wonders of nature

Over 30 antique microscopes are shown, most from the 18th century, in a large variety, with different solutions for lighting the subject and minimization of lens defects (e.g. chromatic aberration): simple, compound and reflecting microscopes, so called English microscopes (renowned for their quality), solar microscopes (which project their image on a wall, using sunlight only). Several wooden cabinets with microscopic slides are testimony of the craftsmanship than went into collections of ready made samples, which at the time were highly fashionable among well-to-do citizens who took an interest in scientific developments.

7 Collection: The Albinus Brothers

The room is dedicated to famous 18th-century anatomist Bernhard Siegfried Albinus and his brother and successor Frederik Bernhard Albinus, showing a few of the over 750 wet and dry anatomical samples that Bernhard Siegfried collected, and a wide variety of medical instruments (most 1670–1700) collected by his brother: several amputation saws and knives, cauterizing irons, a wide variety of forceps and clamps, spatulas, an elevator, a bullet extractor and brace, several (drill) crowns, two drills, a lenticular, several elevatoriums, a chuck key, a coach screw, a retractor, lithotomy scoops, a Phimosis knife, gorgerets, a catheter, a bistoury cache, a combined syringotome and seton needle, a wound retractor, lithotomy directors, probes, a tobacco enema

8 Collection: Sebaldus Justinus Brugmans

Sebald Justinus Brugmans was a Dutch botanist, physician and professor of natural sciences. As an army physician he became notable for his battle against unsanitary conditions, and spread of contagious diseases. The room shows a large collection of fish skins ('the protected body'), human skulls (some affected by accident or disease), animal skulls (mainly birds) and a variety of other anatomic samples, including some foetuses in a jar.

10 Hendrik Bosch's collection of medicine, Butterfly cabinet

The room houses a large simples cabinet (1760), from Amsterdam physician Hendrik Bosch. Also a large cabinet with butterflies (1760) (content lost) from Christiaan Sepp and son, who published a work on butterflies and insects in several volumes (1762–1860).