Mary Townsend may refer to:
Mary Townsend (entomologist) (1814–1851), American abolitionist and entomologist Mary Townsend (artist) (1822–1869), New Zealand artist Mary Ashley Townsend (1836–1901), American poet Mary Elizabeth Townsend (1841–1918), British philanthropist and co-founder of the "Girls' Friendly Society" Mary Townsend Seymour (1876–1957), African-American politician