Nick Kyrgios defeated Yoshihito Nishioka in the final, 6–4, 6–3 to win the men's singles tennis title at the 2022 Washington Open. It was his second Washington title, following 2019. Kyrgios saved five match points en route to the title, in the quarterfinals against Frances Tiafoe. He also did not drop serve during the tournament.
Jannik Sinner was the reigning champion, but did not compete.
Seeds All seeds received a bye into the second round.
Draw
Finals
Top half Section 1
Section 2
Bottom half Section 3
Section 4
Qualifying Seeds
Qualifiers
Draw
First qualifier
Second qualifier
Third qualifier
Fourth qualifier
Fifth qualifier
Sixth qualifier
References
External links Main draw Qualifying draw