Alphabet murders are a 1970s series of child murders in the surroundings of Rochester, New York (United States).
Alphabet murders may also refer to:
Crime California alphabet murders, a series of late-20th-century murder-rapes in California committed by Joseph Naso
Other uses The Alphabet Murders (poem), a 1976 poem by John Tranter The Alphabet Murders (film), a 1965 UK film based on the Agatha Christie story The ABC Murders
See also ABC Murders (disambiguation) The Alphabet Killer (film), a 2008 US horror film based on the 1970s New York alphabet murders