Patrick or Pat Spencer may refer to:
Patrick Spencer (cyclist) (fl. 1976), Antiguan cyclist Patrick Spencer (politician) (born 1988), British politician Pat Spencer (born 1996), American basketball and collegiate lacrosse player Pat Spencer (General Hospital), fictional character in the TV series General Hospital
See also Patricia Spencer (1953–?), American teenager who disappeared in 1969; see Disappearance of Patricia Spencer and Pamela Hobley