Schloss is a German surname. Notable people with the surname include:
Adolphe Schloss (1842–1910), German-French art collector Andrew Schloss (born 1952), American musician and computer engineer Arleen Schloss (1943–2026), American performance artist Cynthia Schloss (1948–1999), Jamaican singer Edith Schloss (1919–2011), American painter Eva Schloss (1929–2026), Austrian-English Holocaust survivor and memoirist Glenn Schloss (born 1972), American drummer Irene Schloss, Argentinian Antarctic researcher Jeremy Schloss (born 1973), Australian rugby player Patrick Schloss, American rehabilitation psychologist, educator, professor and university administrator Peter Schloss, Chinese-based businessman Ruth Schloss (1922–2013), Israeli painter and illustrator Sophia Mitri Schloss (born 2002), American actress Walter Schloss (1916–2012), American investor, fund manager and philanthropist Zander Schloss (born 1961), American musician, actor and composer