Bufford is a surname. Notable people with the name include:
Charles Lee Bufford (born 1953–54), American man cleared of murder Jamall Bufford, American rapper known as "Buff1" John Henry Bufford (1810–1870), American lithographer Joseph Henry Bufford (c.1854-1923), American state legislator
See also Buford (surname) Burford (surname) Bluford (disambiguation) Bruford (disambiguation)