Pierozzi is a surname of Italian origin. Notable people with the surname include:

Antonio Pierozzi (1389–1459), saint by the Catholic Church Caterina Angela Pierozzi (c. 1670–1690), Italian painter active in Florence Edoardo Pierozzi (born 2001), Italian football player Giuseppe Pierozzi (1883–1956), Italian stage and film actor Orazio Pierozzi (1884–1919), World War I flying ace

See also Piero (disambiguation) Pierazzi