Biohazard 4 may refer to:
Resident Evil 4, 2005 video game Resident Evil 4 (2023 video game), remake of the 2005 video game Resident Evil: Afterlife, the fourth live-action film in the Resident Evil series, released in 2010. Resident Evil: Death Island, the fourth CG film in the Resident Evil series, releasing in 2023 Biohazard level 4, category to distinguish the severity of biological agents