O'Daniel may refer to:
Dorian O'Daniel (born 1994), American football linebacker Ed O'Daniel (born 1938), American politician in the state of Kentucky John W. O'Daniel (1894–1975), aka "Iron Mike", a senior United States Army officer in World War I, World War II and the Korean War Nicky O'Daniel, American actress on stage and screen W. Lee O'Daniel, aka "Pappy" O'Daniel (1890–1969), American Democratic Party politician from Texas and radio host William L. O'Daniel (1923–2017), American farmer and politician
See also W. Lee O'Daniel (and the Light Crust Dough Boys)", a song written by James Talley and originally recorded by Johnny Cash Pat O'Daniel and His Hillbilly Boys, Texan Western swing band with its own radio program during the mid-1930s Daniel (disambiguation)